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Document Date: Oct/28/2025

Dairy cow- and avian-origin clade 2.3.4.4b H5N1 induce severe mastitis in lactating goats and transmission to suckling goats

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Alkie et al. (2025) listed the following highlights from their research:

  • "Cow- and avian-origin A(H5N1) caused severe mastitis in goats
  • Infected goats shed viruses in milk, transmitting A(H5N1) to suckling kids
  • Both viruses infected goat respiratory and mammary cells, which express sialic acid receptors
  • Findings show underestimated A(H5N1) risk in ruminants, urging better livestock surveillance"
h5n1
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hpai
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lactating goats
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intrammamary